Isaac Mullins was born in Somerset around 1781. He was a glove manufacturer and was in partnership with John Bide in the company of Bide & Mullins with a glove manufactory in Reckleford. It was listed in Pigot's Directory of 1824. Isaac Mullins parted company with John Bide by mutual consent in 1828 and a notice to this effect was posted in the London Gazette.
Mullins was listed under his own name in Pigot's directory of 1830 as a glove manufacturer in Kiddles Lane (now Eastland Road). He was also listed in the poll books of 1832 and 1834 by virtue of living at Kiddles Lane as well as being the occupier of property there.
In 1837, as a result of actions brought by his creditors, he was declared bankrupt.
The 1841 census listed Isaac, described simply as a glover, aged 60 living in Kiddles Lane, in one of only three properties there at this time. Living with him was his 20-year-old son James, a glover foreman.
In April 1845 Isaac Mullins gave evidence at the prosecution of Nehemiah Edwards who received twelve months imprisonment "for stealing five fowls, the property of Isaac Mullins" as reported in the Dorset County Chronicle.
Isaac Mullins died in Yeovil in the autumn of 1846 aged 65.